Association between RS266729 polymorphism of adiponectin ge

Association between RS266729 polymorphism of adiponectin gene with type 2 diabet in diabetic patients in jahrom city

• A signaling molecule that is secreted from white and brown adipose tissue.
• Composed of 247 amino acids.
• Accounts for 0.05 % of total serum protein.
• Concentration: 2~20 μg/mL in the blood
• The gene for adiponectin is located on chromosome 3q27.
• This region of the chromosome has also been linked to type 2 diabetes.
• A SNP located 276 base pairs downstream of the start site of the adiponectin gene was associated with increased insulin resistance and risk of developing type 2 diabetes.